Research in Genetics in the Department of Biological Sciences is fundamental to the advancement of biological knowledge at all levels of organization, from molecules to populations. The Department of Biological Sciences has a number of research programs that have a strong genetic focus, using a variety of systems - both prokaryotic and eukaryotic - that offer unique challenges. For example, characterization of yeast mutants tease apart the fundamentals of eukaryotic transcription, and surveys of conditional mutants in Mycobacteria identify essential genes in this deadly pathogen.